水质 在含水介质中生物降解能力后续评估用贫水可溶性有机化合物的制备和处理指南

[中文适用范围]： 本文件规定了制备水溶性差的有机化合物（即液体和固体化合物）的技术，这些化合物在水中的溶解度小于约100毫克/升，并将其引入测试容器中，以便使用标准方法在水介质中进行随后的生物降解性测试。 随后的生物降解性测试主要是使用 ISO 9439 中描述的释放二氧化碳分析和 ISO 9408 中描述的氧气测定方法，并遵循 ISO 10707 的通常预防措施。 因此，人们可以注意到测量去除率的方法溶解有机碳 (DOC) 的含量不合适。 本文件没有规定生物降解试验方法。 它仅限于描述将测试化合物引入测试介质并使其保持分散状态的技术[4]。 这些技术是在观察评估生物降解性的标准化方法中描述的实验条件的同时实施的。 ISO 9439 基于二氧化碳释放，不适用于测试挥发性化合物。 本文件中描述的一些制备方法可能不会被监管机构接受，无法对测试化合物的可生物降解性做出结论。 生物降解性曲线的示例在附录 A 中给出。 [外文原描述]： This document specifies techniques for preparing poorly water-soluble organic compounds (i.e. liquid and solid compounds) with a solubility in water of less than approximately 100 mg/l and introducing them into test vessels for a subsequent biodegradability test in an aqueous medium using standard methods. The subsequent tests on biodegradability are primarily methods using the analysis of the released carbon dioxide described in ISO 9439 and the determination of the oxygen described in ISO 9408 and following the usual precautions for ISO 10707. Thus, one can notice that the methods measuring the removal of dissolved organic carbon (DOC) are not appropriate. This document does not specify the biodegradation test methods. It is restricted to describing techniques for introducing the test compounds into the test medium and to keeping them in a dispersed state [4] . These techniques are implemented while observing the experimental conditions described in the standardized methods for evaluating biodegradability. ISO 9439, based on CO2 evolution, is not suitable for testing volatile compounds. Some of the preparation methods described in this document might not be accepted by regulators for making conclusions on the ready biodegradability of tested compounds. Examples of biodegradability curves are given in Annex A.