室内空气.第39部分:胺的测定.用（超）高效液相色谱结合高分辨率或串联质谱法分析胺

[中文适用范围]： 本文件与 ISO 16000-38 一起规定了使用累积采样和高效液相色谱 (HPLC) 结合串联质谱 (MS-MS) 或高分辨率质谱 (HRMS) 测定室内空气中一级、二级和三级脂肪族和芳香族胺的质量浓度的测量方法。本文件涵盖了分析程序。ISO 16000-38 涵盖了采样程序和采样器的制造。本文件描述了胺的色谱和质谱规范。测量结果以 µg/m3 表示。虽然主要用于测量表 A.1 和 A.2 中列出的胺，但它也可以用于测量室内空气中的其他胺。本文件给出了说明并描述了加入其他胺的程序。本文件关于室内空气中胺类浓度的应用范围取决于校准线的线性范围，因此也取决于气体样品体积（此处：从 5 l 到 100 l）、洗脱液体积（从 1 ml 到 5 ml）、注射体积（从 1 µl 到 10 µl）和分析设备的灵敏度（例如线性范围从 2 pg 到 2 ng 胺）。对于表 A.1 和 A.2 中列出的大多数胺类，对于常用分析设备（例如 Waters“TQD”），应用范围预计约为 0.002 µg/m3（100 l 样品）至 2000 µg/m3（5 l 样品）。与普通胺类分析相比，乙醇胺衍生物的分析灵敏度通常高出约 10 倍，而短链脂肪胺的分析灵敏度通常低约 10 倍。分析方法的性能数据在附录 B 中给出，特别是表 B.1 和 B.2。如果检测限足够，本文件也可用于测定水中的胺。本文件不涉及室内空气（也不涉及水样）中异氰酸酯作为相应胺的测定（由 ISO 17734-1 和 ISO 17734-2 涵盖）。 [外文原描述]： This document, along with ISO 16000-38, specifies the measurement method for determining the mass concentration of primary, secondary and tertiary aliphatic and aromatic amines in indoor air using accumulated sampling and high-performance liquid chromatography (HPLC) coupled with tandem mass spectrometry (MS-MS) or high-resolution mass spectrometry (HRMS). The analytical procedure is covered by this document. The sampling procedure and the manufacturing of the samplers are covered by ISO 16000-38. This document describes specifications for the chromatography and the mass spectroscopy for the amines. Measurement results are expressed in µg/m3. Although primarily intended for the measurement of amines listed in Tables A.1 and A.2, it can also be used for the measurement of other amines in indoor air. This document gives instructions and describes procedures for the inclusion of other amines. The range of application of this document concerning the concentrations of amines in indoor air depends on the linear range of the calibration line and hence on the gas sample volume (here: from 5 l up to 100 l), the eluate volume (from 1 ml up to 5 ml), the injection volume (from 1 µl up to 10 µl) and the sensitivity of the analytical equipment (e.g. linear range from 2 pg up to 2 ng amine). The range of application can be expected to be from approximately 0,002 µg/m3 (100 l sample) up to 2 000 µg/m3 (5 l sample) for a common analytical equipment (e.g. Waters ?TQD") for the majority of the amines listed in Tables A.1 and A.2. The analysis of derivatives of ethanolamine is usually about 10 times more sensitive and the analysis of short-chained aliphatic amines is usually about 10 times less sensitive than the analysis of an average amine. The performance data of the analytical method is given in Annex B, particularly in Tables B.1 and B.2. This document can be used also for the determination of amines in water if the detection limit is sufficient. This document does not cover the determination of isocyanates in indoor air (nor in water samples) as corresponding amines (covered by ISO 17734-1 and ISO 17734-2).