纳米技术.评估固有纳米物体毒性的体外测定用纳米物体工作悬浮液的特性

[中文适用范围]： 本文件描述了在进行体外测定以评估纳米物体固有毒性时要考虑的纳米物体工作悬浮液的特征。 此外，该文件还确定了这些特性的适用测量方法。 本文件适用于纳米物体及其大于 100 nm 的聚集体和团聚体。 本文件旨在帮助澄清观察到的毒性效应是来自测试的纳米物体本身还是来自不受控制的来源。 [外文原描述]： This document describes the characteristics of working suspensions of nano-objects to be considered when conducting in vitro assays to evaluate inherent nano-object toxicity. In addition, the document identifies applicable measurement methods for these characteristics. This document is applicable to nano-objects, and their aggregates and agglomerates greater than 100 nm. This document intends to help clarify whether observed toxic effects come from tested nano-objects themselves or from uncontrolled sources.