标准摘要
[中文适用范围]： 本文件的目的是概述使用丝裂原刺激的外周血淋巴细胞进行双着丝粒测定和质量控制措施的最低要求，以对涉及大规模伤亡情况的个体进行初步评估。 双着丝粒测定是利用染色体损伤来快速估计个体所接受的大致辐射剂量，以补充伤亡的早期临床分类。 本文件重点介绍在初始评估模式中应用双着丝粒测定的组织和操作方面。 双着丝粒测定的技术方面可以在 ISO 19238 中找到。 本文件既适用于经验丰富的单独工作的生物剂量测定实验室，也适用于合作实验室网络（如第 7 条中所定义）。 [外文原描述]： The purpose of this document is to give an overview of the minimum requirements for performing the dicentric assay with quality control measures using mitogen stimulated peripheral blood lymphocytes for initial assessment of individuals involved in a mass casualty scenario. The dicentric assay is the use of chromosome damage to quickly estimate approximate radiation doses received by individuals in order to supplement the early clinical categorization of casualties. This document focuses on the organizational and operational aspects of applying the dicentric assay in an initial assessment mode. The technical aspects of the dicentric assay can be found in ISO 19238. This document is applicable either to an experienced biological dosimetry laboratory working alone or to a network of collaborating laboratories (as defined in Clause 7).
英文名称Radiation protection — Performance criteria for laboratories performing initial cytogenetic dose assessment of mass casualties in radiological or nuclear emergencies — General principles and application to dicentric assay