水质.水中全氟烷基和多氟烷基物质（PFAS）的测定.固相萃取和液相色谱-串联质谱法（LC-MS/MS

[中文适用范围]： 本文件规定了非过滤水中选定的全氟烷基和多氟烷基物质（PFAS）的测定方法，例如饮用水、天然水（淡水和海水）和固体颗粒物质含量低于2克/升的废水(SPM) 使用液相色谱-串联质谱 (LC-MS/MS)。 通过该方法监测的化合物通常是直链异构体。 通过该方法测定的化合物组代表了多种 PFAS。 表 1 中指定的分析物可通过此方法测定。 该列表可以根据该方法的预期目的进行修改。 该方法的下限应用范围可能会根据所用设备的灵敏度和样品的基质而变化。 对于本文件适用的大多数化合物，可以达到 ≥0.2 ng/l 作为定量限。 实际水平可能取决于各个实验室实现的空白水平。 不排除该方法对表 1 中未列出的其他物质或其他类型的水的适用性，但旨在针对每种情况单独进行验证。 注 1：本文件中使用 PFAS 来描述所监测的分析物。 表 1 中的许多化合物都是全氟烷基，也被视为多氟烷基物质。 注 2：本文件中规定了直链 PFAS 异构体。 支链异构体可能存在于环境样品中，尤其是全氟辛烷磺酸。 附录 E 提供了单个异构体的色谱和光谱分离分析方法的示例。 [外文原描述]： This document specifies a method for the determination of selected perfluoroalkyl and polyfluoroalkyl substances (PFAS) in non‑filtrated waters, for example drinking water, natural water (fresh water and sea water) and waste water containing less than 2 g/l solid particulate material (SPM) using liquid chromatography-tandem mass spectrometry (LC‑MS/MS). The compounds monitored by this method are typically the linear isomers. The group of compounds determined by this method are representative of a wide variety of PFAS. The analytes specified in Table 1 can be determined by this method. The list can be modified depending on the purpose for which the method is intended. The lower application range of this method can vary depending on the sensitivity of the equipment used and the matrix of the sample. For most compounds to which this document applies ≥0,2 ng/l as limit of quantification can be achieved. Actual levels can depend on the blank levels realized by individual laboratory. The applicability of the method to further substances, not listed in Table 1, or to further types of water is not excluded, but is intended to be validated separately for each individual case. NOTE 1 PFAS is used in this document to describe the analytes monitored. Many of the compounds in Table 1 are perfluoroalkyl and are also considered polyfluoroalkyl substances. NOTE 2 The linear PFAS isomers are specified in this document. The branched isomers can be present in environmental samples, especially for PFOS. Annex E provides an example of an analytical approach to the chromatographic and spectroscopic separation of individual isomers.