牛奶、奶制品和婴儿配方奶粉.用液相色谱法和串联质谱法（LC-MS/MS）测定三聚氰胺和三聚氰酸

[中文适用范围]： 本文件规定了液相色谱与串联质谱联用 (LC-MS/MS) 测定三聚氰胺和三聚氰酸的方法。 该方法已在实验室间研究中通过分析添加了 0.71 mg/kg 至 1 毫克/千克的婴儿配方奶粉、大豆婴儿配方奶粉、奶粉、全脂牛奶、大豆饮料和牛奶巧克力的样品得到验证。 三聚氰胺为 43 毫克/千克，三聚氰酸为 0.57 毫克/千克至 1.45 毫克/千克。 食品中三聚氰胺和三聚氰酸的定量限 (LOQ) 分别为 0.05 mg/kg 和 0.25 mg/kg。 三聚氰胺的工作范围上限为 10 mg/kg，三聚氰酸的工作范围上限为 25 mg/kg。 [外文原描述]： This document specifies a method for the determination of melamine and cyanuric acid with liquid chromatography in combination with tandem mass spectrometry (LC-MS/MS). The method has been validated in an interlaboratory study via the analysis of spiked samples of milk-based infant formula, soy-based infant formula, milk powder, whole milk, soy drink and milk chocolate ranging from 0,71 mg/kg to 1,43 mg/kg for melamine and 0,57 mg/kg to 1,45 mg/kg for cyanuric acid. The limits of quantification (LOQ) for melamine and cyanuric acid in food are 0,05 mg/kg and 0,25 mg/kg, respectively. The upper limit of the working range is up to 10 mg/kg for melamine and up to 25 mg/kg for cyanuric acid.