标准摘要
[中文适用范围]： 本国际标准描述了使用鲎试剂（LAL）对用于细胞基体外生物测试系统的纳米材料进行评估的应用。该测试适用于分散在水性介质（例如水、血清或反应介质）中的纳米材料样品，以及在与纳米材料在 37 °C 下孵育适当时间后的此类介质。本国际标准仅限于体外系统的测试样品，但该方法也可用于通过静脉途径给药的纳米材料。 [外文原描述]： ISO 29701:2010 describes the application of a test using Limulus amebocyte lysate (LAL) reagent for the evaluation of nanomaterials intended for cell-based in vitro biological test systems. The test is suitable for use with nanomaterial samples dispersed in aqueous media, e.g. water, serum or reaction medium, and to such media incubated with nanomaterials for an appropriate duration at 37 °C. ISO 29701:2010 is restricted to test samples for in vitro systems, but the methods can also be adapted to nanomaterials to be administered to animals by parenteral routes.
英文名称Nanotechnologies — Endotoxin test on nanomaterial samples for in vitro systems — Limulus amebocyte lysate (LAL) test